UW Medicine Faculty Present the Leading Edge of Research

Since its launch in 1976, the Science in Medicine Lecture Series has recognized the School of Medicine faculty research achievements and provided an opportunity for researchers to explore topics outside of their immediate fields.

Lectures are organized into the four categories described below. Speakers are nominated by members of the School of Medicine scientific community and final selection is determined by a committee of peers from the Council on Research and Graduate Education (CORGE).

Science in Medicine Lecture Series

Peer-selected UW Medicine faculty present lectures on the forefront of research.

New Investigator Lectures | The New Investigator Lectures provide an important forum for the recognition of exceptional junior faculty members’ current scientific research.

Science in Medicine Lectures | Science in Medicine Lecturers recognizes the body of research for established faculty members as well as recent exciting discoveries.

Distinguished Scientist Lecture | The Distinguished Scientist Lecture recognizes an accomplished School of Medicine senior faculty member, honoring outstanding achievements in their field of research.

Annual Lecture | The Annual Lecture recognizes a prominent, nationally recognized scientist from another research institution, whose research has had a profound impact on their field.

Upcoming Science in Medicine lecture:

“Meet the neighbors: A universal technology for probing RNA-interactions and RNA-scaffolded subcellular compartments in situ”

Date: December 14, 2022, at 11 AM – 12 PM

Zoom Webinar: https://washington.zoom.us/j/94084786076

David Shechner, PhD

Assistant Professor, Department of Pharmacology

Dr. Shechner is an Assistant Professor in the Department of Pharmacology at UW. His laboratory seeks to understand how RNA molecules help to organize subcellular compartmentalization, and how these cryptic architectural functions are perturbed throughout various human pathologies. Towards this goal, the Shechner lab specializes in developing new chemical biology and genomics tools for probing and manipulating RNA functions in situ. Their flagship project has been the development of O-MAP, is a nearly universal method for elucidating the proteins, transcripts, and genomic loci surrounding nearly any RNA of interest, and in nearly any biological setting, with exceptional precision. With this powerful new approach in hand, they now aim to decipher the molecular mechanisms by which RNAs scaffold subcellular structures like nucleoli and Barr bodies, and how nascent transcripts modulate and functionalize nuclear architecture. Deciphering these longstanding, previously intractable questions will reveal fundamental principles driving subcellular architecture, and facilitate the discovery of novel biomarkers and therapeutic targets in heart disease, developmental disorders, and cancer.